Surgical Treatment and Molecular Marker Exploration of Locally Recurrent Colorectal Cancer

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Observational
SUMMARY

This study intends to explore the clinicopathological characteristics and survival prognosis of locally recurrent colorectal cancer patients with different treatment modes by retrospectively analyzing the medical records of locally recurrent colorectal cancer patients who received hospitalization in our center. Transcriptome sequencing and public databases were used to screen for molecular markers related to locally recurrent colorectal cancer and to explore molecular markers' regulatory role in the progression of locally recurrent colorectal cancer.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
View:

• Patients with LRCRC who received hospitalization in our center and patients with stage II-III colorectal cancer whose primary surgery was radical surgery

• The pathological type of primary tumor is adenocarcinoma

• Postoperative local recurrence of colorectal cancer diagnosed by imaging or pathological examination

• Have complete medical records and continuous follow-up records

Locations
Other Locations
China
Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
RECRUITING
Beijing
Contact Information
Primary
Fei Huang, M.D.
frankhuangxm@outlook.com
86-010-87787670
Time Frame
Start Date: 2023-01-30
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 500
Treatments
patients with local recurrence
patients without local recurrence
Related Therapeutic Areas
Sponsors
Leads: Cancer Institute and Hospital, Chinese Academy of Medical Sciences

This content was sourced from clinicaltrials.gov